Tumor-targeting properties of novel immunocytokines based on murine IL1β and IL6
نویسندگان
چکیده
منابع مشابه
Tumor-targeting properties of novel immunocytokines based on murine IL1β and IL6.
There is an increasing biotechnological interest in 'arming' therapeutic antibodies with bioactive payloads. Many antibody-cytokine fusion proteins (immunocytokines) have been described and some of these biopharmaceuticals have progressed to clinical studies. Here, we describe for the first time the expression and in vivo characterization of immunocytokines based on murine IL1β and IL6. These p...
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ژورنال
عنوان ژورنال: Protein Engineering, Design and Selection
سال: 2014
ISSN: 1741-0134,1741-0126
DOI: 10.1093/protein/gzu013